【Danruo Bangkok Success Story】A Fertility Journey from “Empty Follicles” in the US to a High-Grade (4AA) Embryo at Danruo Bangkok

 basic information

 Woman's age: 34 years old

 AMH: 0.22 - 0.8 ng/mL (multiple tests, all low ovarian reserve)

 Marriage and childbearing history: Having a child by yourself

 Menstruation cycle: Regular (26 - 28 days)

 Past medical history/allergic history/family genetic disease history: none

 Difficulties overseas: The shadow shrouded in "empty eggs"

 Because the AMH was as low as 0.22-0.8 and there was a need for a second child, she went to the United States to test tube and found "12 follicles" for the first time. The plan given by American doctors is as follows:

 High-dose Gonal-F: 300 - 375 IU/day × more than 10 days

 High-dose combined oral administration of Clomid+Tamoxifen: 100mg/day +40 mg/day (first 5 days)

 Although the plan seemed to be "full fire", the final result was disappointing-"only 3 eggs were taken and all were empty."

 Dan Ruo breaks the game: A counterattack journey under AMH≈0.5

 February 2025 Dan Ruo's first diagnosis evaluation

 The doctor accurately pointed out the key issue: "Your AFC is not bad. The core problem is the low egg maturity rate."

 Xue Bo formulated targeted strategies: "Increase the proportion of mature eggs and adopt PPOS promotion plan"

 Three-stage dismantling of Danruo's "maturity rate improvement strategy"

 Preconditioning stage (before going to Thailand,~ February 16)

 Combined with the patient's hormone data and comprehensive judgment of ovarian response, there is no need to use down-regulating drugs or advance pretreatment. It was assessed that although AMH was low but not in absolute ovarian failure, gentle stimulation was appropriate.

 Emission promotion stage (February 16 - 25)

 Slow escalation: The starting dose of Gonal-f is 150 IU, and will be increased in the later period according to circumstances

 Simultaneous control of LH peak: Oral administration of dydrogone suppresses the risk of "premature ovulation" in follicles throughout the process

 Add GnRH antagonist Szekai in the middle and late stages to ensure the best time window for egg retrieval

 Highlights of remote management:

 Home injection + WeChat daily feedback on monitoring results

 The medical assistant accurately calculates the night acupuncture time and plans in advance for egg retrieval and travel to Thailand.

 -** Oocyte retrieval and laboratory culture (Oocyte retrieval on February 25)**

 Mature egg rate soared from 0% to 80%(5 retrieved eggs, 4 mature eggs)

 Number of blastocysts: 3 (including 4AA high-quality embryos)

 expert interpretation

 Danruo Laboratory's advanced technology + dynamic and precise adjustment of cycle + efficient collaboration of remote services can significantly improve patients 'mature egg proportion, embryo quality and overall confidence in the cycle.

 Case inspiration: Choosing the right platform is the key in the battle to defend fertility

 Even if AMH is low and has experienced failures, a professional medical team + top-notch laboratory technology + warm service system can still rewrite the birth outcome. Thailand's Tanruo Reproductive Hospital uses science as the pen and professionalism as the ink to write a wonderful chapter of counterattack on the fertility questionnaires of patients with low AMH, making every fertility dream possible to bloom.