【Danruo Bangkok Success Story】A New Direction in Fertility Care: Finding Hope at Danruo Bangkok After Cross-Border Challenges

"Japan took 22 eggs twice, but only 3 were ripe! This time, 8 eggs →6 eggs matured, and the mature egg rate went from 13.6% to 75%. I'm so happy! Fortunately, I transferred here to do it."

Comparison of periodic data between China and Japan

Basic information

Woman's age: 41 years old

Blood group: Type O, Rh positive

AMH: 1.46 ng/ml (fluctuations 0.8 - 2.3)

Antral follicle count (AFC): 10+

Menstruation cycle: Basic regularity (26 - 28 days), occasionally prolonged

Past medical history/allergic history/family genetic disease history: none

From "egg laying machine" to "mature egg hunter"

Japan's dilemma: The neglected "mature egg trap"

2024.07 First Japanese cycle: 8 follicles →3 eggs (containing 1 immature MI egg) →1 blastocyst (not screened)

2024.11 Second Japanese cycle: 14 follicles →3 mature eggs (maturation rate 21.4%) →2 blastocysts (1 screened)

Thailand's Tanruo broke the game: the change from "quantity" to "quality"

2025.02 Dan Ruo's first visit: The doctor pointed out the key: "Your AFC (10+) is not bad, but egg maturity disorder is the main reason."

Xuebo's strategy: "There is room for improvement in ovulation promotion, and PPOS promotion plan will improve maturity rate"

Technical disassembly: How did Dan Ruo increase the maturity rate by five times?

Three-stage maturity management

Preconditioning stage (before February 16 before going to Thailand): After diagnosis by a doctor, no pretreatment is required

Emission promotion stage (February 16 - 25)

PPOS solution core

Slow stimulation: Gonal-f started at 150 IU and was adjusted to 225 IU later

Dydrogstrone suppresses LH spike (avoids "premature ovulation" of follicles)

Add Szekai 0.25mg (GnRH antagonist) in the middle and late stages

Oocyte retrieval stage (February 23 - 27)

Embryo culture and PGT-A screening

ICSI fertilization: All 6 mature eggs were fertilized

Blastocyst formation: A total of 3 blastocysts were obtained (Day5×2, Day 6 ×1)

PGT-A chromosome screening result: 5BB embryo (Day5) is normal

Key node

MII eggs: Only MII eggs are fertile

Cleavage synchronization rate: 8 cells on Day3, indicating that the development potential is consistent

5BB blastocyst: "5" represents the degree of expansion,"BB" represents the internal cell mass/trophoblast rating

Cross-border cycle: 9 days to complete the "Shanghai-Bangkok" miracle Timeline

2.16: Shanghai has menstruation and launched the PPOS solution

2.21: B-ultrasound in a third-level hospital in Shanghai: 7 follicles of 13 - 16mm, hormones: E2 = 2150pg/ml (indicating good follicle maturity)

2.23: Shanghai Pudong Airport → Bangkok Suvarnabhumi, Thailand Tanjung Airport transfer to hotel, Xue Bo online attention to guests to reach airport and hotel information

2.24: Visit by Dr. Jariya before egg retrieval in Danjak, Thailand

2.25: Thailand Danruo according to the results of follow-up visit, get egg protection needle

2.26: Thailand Danruo Night Acupuncture

2.27: 8 eggs retrieved in Tanruo, Thailand →6 MII→ ICSI completed the same day

Expert interpretation: Mature egg rate is more important than the number of eggs retrieved

Danruo embryologist Xue Bo said: "The ovaries of 40+ women are like 'old orchard'. Instead of picking 10 green apples, it is better to wait for 3 red apples. We use hormone regulation + maturity monitoring to make each follicle 'ripe' at the most appropriate time point."

medical evaluation

A 41-year-old woman completed a high-quality ovulation promotion cycle under the conditions of low AMH and limited ovarian reserve. The ICSI fertilization rate is 100%, the blastocyst formation rate is 50%, and one PGT normal blastocyst is finally obtained, which has clinical transplant potential. Cycle management is efficient, the cross-border medical treatment process for patients is smooth, and night acupuncture and B-ultrasound monitoring are well coordinated.